Atrial Fibrillation (AF): Patients who have irregular heartbeat (AF) are at increased risk of stroke due to blood clots forming in the heart. Ablation of parts of the electrical circuit in the atria at the top of the heart can restore normal rhythm, but recurrence of AF means that blood thinning has to be continued. 24h ECG monitoring is now practical: the latest sub-matchbox sized devices provide comprehensive autonomic nervous system data, over a Bluetooth link. However, using this mass of data to predict who is at risk of AF requires the kind of complex reasoning made possible by the proposed work in the project.
This case will start in Year 2 of the project as a means of validating the PAMBAYESIAN approach.